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Interleukin-10 gene promoter polymorphism and susceptibility to liver cirrhosis.

Hepato-gastroenterology - 1 Jan 2000

Jin Xue-Yuan, Wang Ya-Qing, Yan Tao, Wang Jianjun, Qing Song, Ding Ning, Tian Hong, Zhao Ping

Abstract excerpt

BACKGROUND/AIMS: Liver cirrhosis is the end-stage of various liver diseases, which has a poor prognosis and determined by deterioration of hepatic functional capacity and consecutive development of hepatic complications. We investigated the role of IL-10-592 A/C, IL-10-819 C/T and IL-10-1082 A/G gene polymorphisms on the development of liver cirrhosis. METHODOLOGY: A 1:2 matched case-control study was conducted,...

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PMID: 24901158

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