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Article

Characterization of novel rad6/ubc2 ubiquitin-conjugating enzyme mutants in yeast.

Current genetics - 1 Apr 2000

Freiberg G, Mesecar A D, Huang H, Hong J Y, Liebman S W

Abstract excerpt

Null mutations in the RAD6/UBC2 gene encoding an E2 ubiquitin-conjugating enzyme cause deficiencies in DNA repair, N-end-rule protein degradation, sporulation and telomeric silencing, and alter the preferred integration positions for Ty1 retrotransposons. Here we selected for mutants of RAD6 that cause a release of telomeric silencing. Some alleles retained nearly wild-type ability for sporulation, DNA repair and...

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PMID: 10803884
DOI: 10.1007/s002940050523

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of novel rad6/ubc2 ubiquitin-conjugating enzyme mutants in yeast.PMID 10803884Read ↗

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