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Article

Rad6-dependent ubiquitination of histone H2B in yeast.

Science (New York, N.Y.) - 21 Jan 2000

Robzyk K, Recht J, Osley M A

Abstract excerpt

Although ubiquitinated histones are present in substantial levels in vertebrate cells, the roles they play in specific biological processes and the cellular factors that regulate this modification are not well characterized. Ubiquitinated H2B (uH2B) has been identified in the yeast Saccharomyces cerevisiae, and mutation of the conserved ubiquitination site is shown to confer defects in mitotic cell growth and...

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Identifiers

PMID: 10642555
DOI: 10.1126/science.287.5452.501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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