Specificities of heparan sulphate proteoglycans in developmental processes.

Abstract excerpt

Heparan sulphate proteoglycans are abundant cell-surface molecules that consist of a protein core to which heparan sulphate glycosaminoglycan chains are attached. The functions of these molecules have remained mostly underappreciated by developmental biologists; however, the actions of important signalling molecules, for example Wnt and Hedgehog, depend on them. To understand both the mechanisms by which ligands...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Body Patterning
• Share to Heparan Sulfate Proteoglycans
• Share to Ligands