Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental roles of heparan sulfate proteoglycans in Drosophila.

Glycoconjugate journal - 1 Jan 2000

Lin Xinhua, Perrimon Norbert

Abstract excerpt

The formation of complex patterns in multi-cellular organisms is regulated by a number of signaling pathways. In particular, the Wnt and Hedgehog (Hh) pathways have been identified as critical organizers of pattern in many tissues. Although extensive biochemical and genetic studies have elucidated the central components of the signal transduction pathways regulated by these secreted molecules, we still do not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Drosophila
Share to Genes, Insect

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hedgehog Proteins

Share to Heparan Sulfate Proteoglycans

Share to Proto-Oncogene Proteins

Share to Wnt Proteins

Share to Zebrafish Proteins

Source

Identifiers

PMID: 12975617
DOI: 10.1023/A:1025329323438

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental roles of heparan sulfate proteoglycans in Drosophila.PMID 12975617Read ↗

Heparan sulphate proteoglycans: the sweet side of development.Semantic proximity Read ↗

Specificities of heparan sulphate proteoglycans in developmental processes.Semantic proximity Read ↗

Drosophila heparan sulfate 6-O endosulfatase regulates Wingless morphogen gradient formation.Semantic proximity Read ↗

In vivo manipulation of heparan sulfate structure and its effect on Drosophila development.Semantic proximity Read ↗

The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors.Semantic proximity Read ↗

HSPG synthesis by zebrafish Ext2 and Extl3 is required for Fgf10 signalling during limb development.Semantic proximity Read ↗

Functional analysis of proteoglycan galactosyltransferase II RNA interference mutant flies.Semantic proximity Read ↗

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.Semantic proximity Read ↗

Shifted, the Drosophila ortholog of Wnt inhibitory factor-1, controls the distribution and movement of Hedgehog.Semantic proximity Read ↗

Mammalian brain morphogenesis and midline axon guidance require heparan sulfate.Semantic proximity Read ↗

Wingless/Wnt signaling in Drosophila: the pattern and the pathway.Semantic proximity Read ↗

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.