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Article

Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.

American journal of physiology. Lung cellular and molecular physiology - 1 May 2000

Mitchell R W, Halayko A J, Kahraman S, Solway J, Wylam M E

Abstract excerpt

We previously demonstrated that after several days of serum deprivation about one-sixth of confluent cultured canine tracheal myocytes acquire an elongated, structurally and functionally contractile phenotype. These myocytes demonstrated significant shortening on ACh exposure. To evaluate the mechanism by which these myocytes acquire responsiveness to ACh, we assessed receptor-Ca(2+) coupling using fura 2-AM...

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PMID: 10781442
DOI: 10.1152/ajplung.2000.278.5.L1091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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