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Article

Serum deprivation induces a unique hypercontractile phenotype of cultured smooth muscle cells.

The American journal of physiology - 1 May 1998

Ma X, Wang Y, Stephens N L

Abstract excerpt

Chronic asthma is characterized by hypertrophy and hyperplasia of airway smooth muscle cells (SMC) that limit airflow by a geometric effect. Whether contractility of airway SMC is altered is not clear. Cultured cells were used as a model of hyperplasia. Phenotypic changes seen indicated conversion to a synthetic, weakly contractile type. At confluence, although limited reversal of protein changes was seen, no...

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Source

Identifiers

PMID: 9612207
DOI: 10.1152/ajpcell.1998.274.5.C1206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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