Article
Primary culture of human atrial myocytes is associated with the appearance of structural and functional characteristics of immature myocardium.
Journal of molecular and cellular cardiology - 1 May 1997
Bénardeau A, Hatem S N, Rücker-Martin C, Tessier S, Dinanian S, Samuel J L, Coraboeuf E, Mercadier J J
Abstract excerpt
We examined changes in the structural and physiological characteristics of human atrial myocytes during primary culture in the presence of serum. Action potentials and ionic currents were recorded in freshly dissociated (FM) and cultured (CM) whole-cell patch-clamped myocytes, alpha-smooth muscle actin, sarcomeric alpha-actinin and beta-myosin heavy chains (beta-MHC) were stained with monoclonal antibodies. From...
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