Article
Ca2+ handling is altered when arterial myocytes progress from a contractile to a proliferative phenotype in culture.
American journal of physiology. Cell physiology - 1 Sept 2008
Berra-Romani Roberto, Mazzocco-Spezzia Amparo, Pulina Maria V, Golovina Vera A
Abstract excerpt
Phenotypic modulation of vascular myocytes is important for vascular development and adaptation. A characteristic feature of this process is alteration in intracellular Ca(2+) handling, which is not completely understood. We studied mechanisms involved in functional changes of inositol 1,4,5-trisphosphate (IP(3))- and ryanodine (Ry)-sensitive Ca(2+) stores, store-operated Ca(2+) entry (SOCE), and...
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