Article
Cell contact as an independent factor modulating cardiac myocyte hypertrophy and survival in long-term primary culture.
Journal of molecular and cellular cardiology - 1 Jan 1998
Clark W A, Decker M L, Behnke-Barclay M, Janes D M, Decker R S
Abstract excerpt
Cardiac myocytes maintained in cell culture develop hypertrophy both in response to mechanical loading as well as to receptor-mediated signaling mechanisms. However, it has been shown that the hypertrophic response to these stimuli may be modulated through effects of intercellular contact achieve...
Topics
- Adrenergic beta-Agonists
- Animals
- Cats
- Cell Communication
- Cell Count
- Cell Culture Techniques
- Cell Survival
- Cells, Cultured
- Female
- Hypertrophy
- Intercellular Junctions
- Isoproterenol
- Male
- Myocardial Contraction
- Myocardium
- Myofibrils
- Phenotype
- Proteins