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Article

Functional characterization of serum- and growth factor-induced phenotypic changes in intact bovine tracheal smooth muscle.

British journal of pharmacology - 1 Oct 2002

Gosens Reinoud, Meurs Herman, Bromhaar Mechteld M Grootte, McKay Sue, Nelemans S Adriaan, Zaagsma Johan

Abstract excerpt

1. The present study aims to investigate whether phenotypic changes, reported to occur in cultured isolated airway smooth muscle (ASM) cells, are of relevance to intact ASM. Moreover, we aimed to gain insight into the signalling pathways involved. 2. Culturing of bovine tracheal smooth muscle (BTSM) strips for up to 8 days in the presence of 10% foetal bovine serum caused a time-dependent (t(1/2)=2.8 days)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12359627
DOI: 10.1038/sj.bjp.0704889
PMCID: PMC1573514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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