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Article

Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair.

Mutation research - 1 Apr 2000

Lindahl T

Abstract excerpt

The chemical instability of the covalent structure of DNA, and in vivo exposure of DNA to reactive oxygen species and endogenously produced alkylating agents, has triggered the evolution of several specific DNA repair pathways. A major strategy of repair involves the initial removal of an altered base from DNA by a member of the enzyme family of DNA glycosylases. The currently known enzymes of this type in...

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Identifiers

PMID: 10767624
DOI: 10.1016/s1383-5742(00)00024-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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