Article
Uracil-DNA glycosylases preferentially excise mispaired uracil.
The Biochemical journal - 1 Nov 1992
Verri A, Mazzarello P, Spadari S, Focher F
Abstract excerpt
We have investigated the substrate specificity of human, viral and bacterial uracil-DNA glycosylases employing as substrate double-stranded oligonucleotides containing in the same position of the 5'-32P-labelled strand an uracil residue facing, on the complementary strand, guanine (mimicking cyto...
Topics
- Animals
- Base Sequence
- DNA
- DNA Glycosylases
- DNA Repair
- Escherichia coli
- HeLa Cells
- Humans
- Kinetics
- Molecular Sequence Data
- Mutation
- N-Glycosyl Hydrolases
- Promoter Regions, Genetic
