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Article

Single nucleotide polymorphism and linkage disequilibrium within the TCR alpha/delta locus.

Human molecular genetics - 12 Apr 2000

Moffatt M F, Traherne J A, Abecasis G R, Cookson W O

Abstract excerpt

Much attention is being given to the identification of common disease genes through whole-genome linkage disequilibrium (LD) screens with single nucleotide polymorphisms (SNPs). Simulation studies have suggested that useful LD is unlikely to extend beyond 3 kb, and that > 500,000 SNPs may be needed for comprehensive coverage of the genome. The TCR alpha/delta locus on chromosome 14q contains many V, J and D...

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PMID: 10767325
DOI: 10.1093/hmg/9.7.1011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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