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Article

Sequence diversity, natural selection and linkage disequilibrium in the human T cell receptor alpha/delta locus.

Human genetics - 1 Apr 2006

Mackelprang Rachel, Livingston Robert J, Eberle Michael A, Carlson Christopher S, Yi Qian, Akey Joshua M, Nickerson Deborah A

Abstract excerpt

T cell receptors (TR), through their interaction with the major histocompatibility complex, play a central role in immune responsiveness and potentially immune-related disorders. We resequenced all 57 variable (V) genes in the human T cell receptor alpha and delta (TRA/TRD) locus in 40 individuals of Northern European, Mexican, African-American and Chinese descent. Two hundred and eighty-four single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16425038
DOI: 10.1007/s00439-005-0111-z

Genes

TRA
TRD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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