Article
Genomic organization and sequence variation of the human integrin subunit alpha8 gene (ITGA8).
Matrix biology : journal of the International Society for Matrix Biology - 1 Nov 2004
Ekwa-Ekoka Catherine, Diaz George A, Carlson Chris, Hasegawa Tomonobu, Samudrala Ram, Lim Kim-Chew, Yabu Julie M, Levy Brynn, Schnapp Lynn M
Abstract excerpt
The integrin alpha8 is highly expressed during kidney and lung development. alpha8-deficient mice display abnormal renal development suggesting that alpha8 plays a critical role in organogenesis. Therefore, it would be of considerable interest to understand the genomic structure, localization and sequence variation of the alpha8 gene. Using FISH and genomic database analysis, we show that alpha8 gene maps to...
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