Article
Systematic study of human alpha beta T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes.
European journal of immunology - 1 Jun 1993
Cornélis F, Pile K, Loveridge J, Moss P, Harding R, Julier C, Bell J
Abstract excerpt
The variation of the alpha beta T cell receptor (TCR) results mainly from rearrangements of germ-line V, D and J elements combined with the processes of N- and P-region addition. In addition to this extensive diversity, diallelic polymorphism is also recognized in V regions of beta loci. Four suc...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Genes
- Haplotypes
- Humans
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Receptors, Antigen, T-Cell, alpha-beta
- Sequence Alignment
- T-Lymphocytes