Article
Allele association studies with SSR and SNP markers at known physical distances within a 1 Mb region embracing the ALDH2 locus in the Japanese, demonstrates linkage disequilibrium extending up to 400 kb.
Human molecular genetics - 12 Dec 2000
Koch H G, McClay J, Loh E W, Higuchi S, Zhao J H, Sham P, Ball D, Craig I W
Abstract excerpt
There has been considerable recent debate concerning the distances over which levels of allelic association useful for genomic quantitative trait locus (QTL) scans can be detected. We have examined simple sequence repeat (SSR) polymorphisms and two single nucleotide polymorphisms (SNPs) in the region flanking the aldehyde dehydrogenase 2 locus, ALDH2, in populations of Japanese alcoholics and controls. These...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.