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Article

Cerebral white matter lesions are not associated with apoE genotype but with age and female sex in Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 May 2000

Sawada H, Udaka F, Izumi Y, Nishinaka K, Kawakami H, Nakamura S, Kameyama M

Abstract excerpt

Cerebral white matter lesions, such as leukoaraiosis, may be a result of damage from cerebral ischaemia, and may also be associated with the degenerative process in Alzheimer's disease. The apolipoprotein epsilon4 (apoepsilon4) genotype is a genetic risk factor for both Alzheimer's disease and ischaemic brain damage through acceleration of atherosclerosis. The aim was to determine whether apoepsilon4 may be...

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Identifiers

PMID: 10766901
DOI: 10.1136/jnnp.68.5.653
PMCID: PMC1736920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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