Article
APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis.
Neurology - 16 Jul 2013
Schilling Sabrina, DeStefano Anita L, Sachdev Perminder S, Choi Seung Hoan, Mather Karen A, DeCarli Charles D, Wen Wei, Høgh Peter, Raz Naftali, Au Rhoda, Beiser Alexa, Wolf Philip A, Romero José Rafael, Zhu Yi-Cheng, Lunetta Kathryn L, Farrer Lindsay, Dufouil Carole, Kuller Lewis H, Mazoyer Bernard, Seshadri Sudha, Tzourio Christophe, Debette Stéphanie
Abstract excerpt
OBJECTIVE: We aimed to examine the association of APOE ε genotype with MRI markers of cerebrovascular disease (CVD): white matter hyperintensities, brain infarcts, and cerebral microbleeds. METHODS: We performed a systematic review and meta-analysis of 42 cross-sectional or longitudinal studies identified in PubMed from 1966 to June 2012 (n = 29,965). This included unpublished data from 3 population-based...
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