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Article

White matter lesions in Alzheimer patients are influenced by apolipoprotein E genotype.

Dementia and geriatric cognitive disorders - 1 Jan 2000

Bronge L, Fernaeus S E, Blomberg M, Ingelson M, Lannfelt L, Isberg B, Wahlund L O

Abstract excerpt

To analyse the influence of apolipoprotein E (APOE) genotype on the extent of white matter lesions (WMLs) in Alzheimer's disease (AD), we examined 60 AD patients with magnetic resonance imaging. The WMLs were rated visually in different brain regions. The patients with the APOE genotype sigma4/4 had more extensive WMLs in the deep white matter than patients with genotypes sigma3/3 and sigma3/4. There was a...

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Source

Identifiers

PMID: 10026381
DOI: 10.1159/000017107

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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