Article
Methylation-dependent melting polymorphisms in genomic fragments of deoxyribonucleic acid.
American journal of obstetrics and gynecology - 1 Apr 2000
Reindollar R H, Fusaris K W, Gray M R
Abstract excerpt
OBJECTIVES: Denaturing gradient gel electrophoresis can detect single base sequence differences in deoxyribonucleic acid and methylation differences in small cloned fragments of deoxyribonucleic acid. We previously detected cell type-specific melting differences by denaturing gradient gel electrophoresis in paired leukocyte and sperm cell samples of deoxyribonucleic acid. We proposed that these differences were...
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