Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chemical gradient-mediated melting curve analysis for genotyping of SNPs.

Electrophoresis - 1 Jul 2009

Russom Aman, Irimia Daniel, Toner Mehmet

Abstract excerpt

This report describes a microfluidic solid-phase chemical gradient-mediated melting curve analysis method for SNP analysis. The method is based on allele-specific denaturation to discriminate mismatched (MM) from perfectly matched (PM) DNA duplexes upon exposure to linear chemical gradient. PM an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to Kinetics
Share to Microfluidic Analytical Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Fluorescence

Share to Nucleic Acid Denaturation

Share to Polymorphism, Single Nucleotide

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 19593749
DOI: 10.1002/elps.200800729
PMCID: PMC2784656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19593749-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chemical gradient-mediated melting curve analysis for genotyping of SNPs.PMID 19593749Read ↗

Rapid melting curve analysis on monolayered beads for high-throughput genotyping of single-nucleotide polymorphisms.Semantic proximity Read ↗

Novel and alternate SNP and genetic technologies.Semantic proximity Read ↗

High-Speed Melting Analysis: The Effect of Melting Rate on Small Amplicon Microfluidic Genotyping.Semantic proximity Read ↗

Spatial DNA melting analysis for genotyping and variant scanning.Semantic proximity Read ↗

Rapid discrimination of single-nucleotide mismatches using a microfluidic device with monolayered beads.Semantic proximity Read ↗

Single nucleotide polymorphism analysis by allele-specific primer extension with real-time bioluminescence detection in a microfluidic device.Semantic proximity Read ↗

High-resolution melting analysis of single nucleotide polymorphisms.Semantic proximity Read ↗

Sub-7-second genotyping of single-nucleotide polymorphism by high-resolution melting curve analysis on a thermal digital microfluidic device.Semantic proximity Read ↗

Microfludic device for creating ionic strength gradients over DNA microarrays for efficient DNA melting studies and assay development.Semantic proximity Read ↗

DNA melting analysis for detection of single nucleotide polymorphisms.Semantic proximity Read ↗

Melting curve analysis of SNPs (McSNP): a gel-free and inexpensive approach for SNP genotyping.Semantic proximity Read ↗

Solution-phase DNA mutation scanning and SNP genotyping by nanoliter melting analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.