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Article

A transgenic insertional inner ear mutation on mouse chromosome 1.

The Laryngoscope - 1 Apr 2000

Friedman R A, Adir Y, Crenshaw E B, Ryan A F, Rosenfeld M G

Abstract excerpt

OBJECTIVES/HYPOTHESIS: To clone and characterize the integration site of an insertional inner ear mutation, produced in one of fourteen transgenic mouse lines. The insertion of the transgene led to a mutation in a gene(s) necessary for normal development of the vestibular labyrinth. STUDY DESIGN: Molecular genetic analysis of a transgene integration site. METHODS: Molecular cloning, Southern and northern...

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Source

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Identifiers

PMID: 10763993
DOI: 10.1097/00005537-200004000-00001
PMCID: PMC3897160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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