Article

Detection of a complex chromosomal rearrangement in a novel mouse mutant by optical genome mapping

2026-04-07

Abstract excerpt

<title>Abstract</title> <p> Here we highlight the utilities of optical genome mapping (OGM) in determining the genomic rearrangements present in a novel transgenic mouse line (Line 781), which expresses the bacterial <italic>lacZ</italic> reporter gene under control of the mouse myelin proteolipid protein ( <italic>Plp1</italic> ) promoter. Hemizygous transgenic mice from Line 781 present with a mutant pheno...

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Literature Corpus work: 71c3ccf0-85ee-54a6-9d13-e639d5235bdd
DOI: 10.21203/rs.3.rs-9271724/v1

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