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Article

Frequent integration of precore/core mutants of hepatitis B virus in human hepatocellular carcinoma tissues.

Journal of viral hepatitis - 1 Mar 2000

Zhong S, Chan J Y, Yeo W, Tam J S, Johnson P J

Abstract excerpt

The development of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) frequently follows persistent HBV infection and may arise in individuals who are hepatitis B e antigen (HBeAg) negative, indicating the possible presence of precore/core mutants. It is unclear whether precore/core mutants are associated with tumour development or are selected for after chromosomal integration of the wild-type...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10760041
DOI: 10.1046/j.1365-2893.2000.00209.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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