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Article

Precore/core mutations of hepatitis B virus in hepatocellular carcinomas developed on noncirrhotic livers.

Gastroenterology - 1 Sept 1996

Minami M, Poussin K, Kew M, Okanoue T, Bréchot C, Paterlini P

Abstract excerpt

BACKGROUND & AIMS: Hepatitis B virus genomes have been detected in hepatocellular carcinoma developed without the pretumoral step of cirrhosis; this finding is consistent with a direct effect of the virus in liver cell transformation. The aim of this study was to investigate the molecular bases for the hepatitis B virus persistence. Three hepatitis B surface antigen-positive and 2 hepatitis B surface...

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Source

Identifiers

PMID: 8780574
DOI: 10.1053/gast.1996.v111.pm8780574

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