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Article

Hepatitis B virus preC mutants in human hepatocellular carcinoma tissues.

Research in virology - 1 Jan 2000

Clementi M, Manzin A, Paolucci S, Menzo S, Bangarelli P, Carloni G, Bearzi I

Abstract excerpt

A comparative analysis of preC sequences of hepatitis B virus (HBV) in human hepatoma (hepatocellular carcinoma; HCC) tissues and non-tumoral liver samples from HCC patients was performed. Ten out of 17 HCC tissue samples exhibited an amino acid substitution at the level of the distal cysteine residue of the HBV preC region, while generation of a TAG translational stop codon was observed in 4 of these samples....

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Source

Identifiers

PMID: 8210712
DOI: 10.1016/s0923-2516(06)80044-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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