Article
Hepatitis B virus preC mutants in human hepatocellular carcinoma tissues.
Research in virology - 1 Jan 2000
Clementi M, Manzin A, Paolucci S, Menzo S, Bangarelli P, Carloni G, Bearzi I
Abstract excerpt
A comparative analysis of preC sequences of hepatitis B virus (HBV) in human hepatoma (hepatocellular carcinoma; HCC) tissues and non-tumoral liver samples from HCC patients was performed. Ten out of 17 HCC tissue samples exhibited an amino acid substitution at the level of the distal cysteine re...
Topics
- Base Sequence
- Carcinoma, Hepatocellular
- Cysteine
- Hepatitis B Core Antigens
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Protein Precursors
- Sequence Homology, Nucleic Acid