Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis.

PloS one - 1 Jan 2012

Jiang Suzhen, Yang Ziwei, Li Weijie, Li Xiaojun, Wang Yongfeng, Zhang Jiangbo, Xu Chunhui, Chen Pei-Jer, Hou Jinlin, McCrae Malcolm A, Chen Xiangmei, Zhuang Hui, Lu Fengmin

Abstract excerpt

To examine the role of hepatitis B virus (HBV) integration in hepatocarcinogenesis, a systematic comparative study of both tumor and their corresponding non-tumor derived tissue has been conducted in a cohort of 60 HBV associated hepatocellular carcinoma (HCC) patients. By using Alu-polymerase chain reaction (PCR) and ligation-mediated PCR, 233 viral-host junctions mapped across all human chromosomes at random,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Chromosome Breakpoints

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Comparative Genomic Hybridization

Share to Genes, Tumor Suppressor

Share to Hepatitis B

Share to Hepatitis B virus

Share to Viral Regulatory and Accessory Proteins

Share to Virus Integration

Source

Open in PubMed Open full text

Identifiers

PMID: 22962577
DOI: 10.1371/journal.pone.0040363
PMCID: PMC3433482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Re-evaluation of the carcinogenic significance of hepatitis B virus integration in hepatocarcinogenesis.PMID 22962577Read ↗

Role of hepatitis B virus DNA integration in human hepatocarcinogenesis.Semantic proximity Read ↗

Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomasSemantic proximity Read ↗

Genomic and oncogenic preference of HBV integration in hepatocellular carcinomaSemantic proximity Read ↗

HBV Integration Induces Complex Interactions between Host and Viral Genomic Functions at the Insertion SiteSemantic proximity Read ↗

The effects of hepatitis B virus integration into the genomes of hepatocellular carcinoma patients.Semantic proximity Read ↗

Cellular Genomic Sites of Hepatitis B Virus DNA IntegrationSemantic proximity Read ↗

HBV Genomic Integration and Hepatocellular CarcinomaSemantic proximity Read ↗

Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus cureSemantic proximity Read ↗

Hepatitis B Virus DNA Integration Drives Carcinogenesis and Provides a New Biomarker for HBV-related HCCSemantic proximity Read ↗

HBV integrations reshaping genomic structures promote hepatocellular carcinomaSemantic proximity Read ↗

Mitochondrial DNA is a frequent target of HBV integrationSemantic proximity Read ↗

The function of targeted host genes determines the oncogenicity of HBV integration in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.