Article
HBV core promoter mutations prevail in patients with hepatocellular carcinoma from Guangxi, China.
Journal of medical virology - 1 Sept 1998
Fang Z L, Ling R, Wang S S, Nong J, Huang C S, Harrison T J
Abstract excerpt
The development of primary liver cancer frequently is associated with persistent HBV infection, and tumours may arise in individuals who are anti-HBe positive. However, it is unclear whether viruses with an HBeAg-negative phenotype are associated with tumour development or are selected, during seroconversion, after chromosomal integration of wild-type viral DNA. In order to investigate the temporal evolution of...
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