Article
Role of hepatitis B virus DNA integration in human hepatocarcinogenesis.
World journal of gastroenterology - 28 May 2014
Hai Hoang, Tamori Akihiro, Kawada Norifumi
Abstract excerpt
Liver cancer ranks sixth in cancer incidence, and is the third leading cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, which arises from hepatocytes and accounts for approximately 70%-85% of cases. Hepatitis B virus (HBV) frequently causes liver inflammation, hepatic damage and subsequent cirrhosis. Integrated viral DNA is found in 85%-90% of...
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