Article
Role of hepatitis B virus DNA integration in human hepatocarcinogenesis.
World journal of gastroenterology - 28 May 2014
Hai Hoang, Tamori Akihiro, Kawada Norifumi
Abstract excerpt
Liver cancer ranks sixth in cancer incidence, and is the third leading cause of cancer-related deaths worldwide. Hepatocellular carcinoma (HCC) is the most common type of liver cancer, which arises from hepatocytes and accounts for approximately 70%-85% of cases. Hepatitis B virus (HBV) frequentl...
Topics
- Carcinoma, Hepatocellular
- Genome, Viral
- Genome-Wide Association Study
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Inflammation
- Liver Neoplasms
- Mutation
- Sequence Analysis, DNA
- Trans-Activators
- Viral Regulatory and Accessory Proteins
- Virus Integration