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Article

XPD polymorphisms: effects on DNA repair proficiency.

Carcinogenesis - 1 Apr 2000

Lunn R M, Helzlsouer K J, Parshad R, Umbach D M, Harris E L, Sanford K K, Bell D A

Abstract excerpt

XPD codes for a DNA helicase involved in transcription and nucleotide excision repair. Rare XPD mutations diminish nucleotide excision repair resulting in hypersensitivity to UV light and increased risk of skin cancer. Several polymorphisms in this gene have been identified but their impact on DNA repair is not known. We compared XPD genotypes at codons 312 and 751 with DNA repair proficiency in 31 women. XPD...

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Identifiers

PMID: 10753184
DOI: 10.1093/carcin/21.4.551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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