Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis.

doi:10.1158/1055-9965.EPI-06-0672

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Polymorphisms in the DNA repair genes XPC, XPD, and XPG and risk of cutaneous melanoma: a case-control analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2006

Li Chunying, Hu Zhibin, Liu Zhensheng, Wang Li-E, Strom Sara S, Gershenwald Jeffrey E, Lee Jeffrey E, Ross Merrick I, Mansfield Paul F, Cormier Janice N, Prieto Victor G, Duvic Madeleine, Grimm Elizabeth A, Wei Qingyi

Abstract excerpt

Sunlight causes DNA damage, including bulky lesions that are removed effectively by the nucleotide-excision repair (NER) pathway. There are at least eight core NER proteins participating in the pathway, and genetic variations in their genes may alter NER functions. We hypothesized that some NER variants are associated with risk of cutaneous melanoma. In a hospital-based case-control study of 602 non-Hispanic...

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PMID: 17164380
DOI: 10.1158/1055-9965.EPI-06-0672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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