Article
Multiple phosphorylation events regulate the subcellular localization of GGA1.
Traffic (Copenhagen, Denmark) - 1 Feb 2004
McKay Melissa M, Kahn Richard A
Abstract excerpt
GGAs comprise a family of Arf-dependent coat proteins or adaptors that regulate vesicle traffic from the trans-Golgi network (TGN). GGAs bind activated Arf, cargo, and additional components necessary for vesicle budding through interactions with their four functional domains: VHS, GAT, hinge, and...
Topics
- ADP-Ribosylation Factors
- Adaptor Proteins, Vesicular Transport
- Animals
- Biomarkers
- COS Cells
- Carrier Proteins
- Chlorocebus aethiops
- DNA-Binding Proteins
- Golgi Apparatus
- HeLa Cells
- Humans
- Mutation
- Phosphorylation
- Protein Structure, Tertiary
- Serine
- Subcellular Fractions
- Threonine
- Vesicular Transport Proteins