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Article

Importance of the Sgs1 helicase activity in DNA repair of Saccharomyces cerevisiae.

Current genetics - 1 Feb 2000

Saffi J, Pereira V R, Henriques J A

Abstract excerpt

The Saccharomyces cerevisiae Sgs1 protein, together with Schizosaccharomyces pombe Rqh1 and the human Bloom and Werner proteins, is a DNA helicase of the Escherichia coli RecQ family. Mutation of SGS1 causes premature aging in yeast cells, including the accumulation of extrachromosomal rDNA circles. We have recently shown that Sgs1p interacts with the DNA repair Rad16p protein and is epistatic to Rad16p for UVC,...

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Identifiers

PMID: 10743562
DOI: 10.1007/s002940050012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Importance of the Sgs1 helicase activity in DNA repair of Saccharomyces cerevisiae.PMID 10743562Read ↗

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