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Article

Interaction of the yeast Pso5/Rad16 and Sgs1 proteins: influences on DNA repair and aging.

Mutation research - 9 Aug 2001

Saffi J, Feldmann H, Winnacker E L, Henriques J A

Abstract excerpt

The interaction trap method was used to isolate putative binding partners of Rad16/Pso5, a protein responsible for repair of silent DNA. One of the interactors found was Sgs1, a DNA helicase influencing the life span of Saccharomyces cerevisiae, with homology to the human BLM, WRN and RECQL4 proteins. Using the same fusion proteins from the two-hybrid screening, we show evidence that both proteins also interact...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11459632
DOI: 10.1016/s0921-8777(01)00093-3

Genes

BLM
RECQL4
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interaction of the yeast Pso5/Rad16 and Sgs1 proteins: influences on DNA repair and aging.PMID 11459632Read ↗

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