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Article

Genetic variation in the B7-1 gene in patients with multiple sclerosis.

Journal of neuroimmunology - 26 Jun 2000

Weinshenker B G, Hebrink D D, Klein C, Atkinson E J, O'Brien P C, McMurray C T

Abstract excerpt

Co-stimulation of T cells by B7-1, a protein that is expressed on antigen presenting cells, favors a T helper type1 (Th1) cellular response. Th1/Th2 bias may influence disease susceptibility or course of MS. We screened the entire coding sequence as well as the 5'- and 3'-untranslated regions of the B7-1 gene using a mutation scanning technique, dideoxyfingerprinting, in DNA from 111 patients with MS from Olmsted...

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Identifiers

PMID: 10742561
DOI: 10.1016/s0165-5728(00)00197-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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