Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic association analysis of the interleukin 7 gene (IL7) in multiple sclerosis.

Journal of neuroimmunology - 1 Dec 2007

Lundmark Frida, Duvefelt Kristina, Hillert Jan

Abstract excerpt

IL7 is a nonredundant cytokine, essential for T cell survival and development in humans. We genotyped nine tagging single nucleotide polymorphisms (SNP), representing all parts of the IL7 gene, in 1,210 Swedish multiple sclerosis (MS) patients and 1,234 healthy controls. None of the SNPs showed a significantly different distribution in MS, and haplotype analysis also failed to reveal differences between patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genotype
Share to Interleukin-7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Sclerosis

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17913246
DOI: 10.1016/j.jneuroim.2007.08.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic association analysis of the interleukin 7 gene (IL7) in multiple sclerosis.PMID 17913246Read ↗

Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis.Semantic proximity Read ↗

Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis.Semantic proximity Read ↗

Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis.Semantic proximity Read ↗

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility.Semantic proximity Read ↗

Variation in the IL7RA and IL2RA genes in German multiple sclerosis patients.Semantic proximity Read ↗

Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis.Semantic proximity Read ↗

Interleukin 7 receptor alpha polymorphism rs6897932 and susceptibility to multiple sclerosis in the Western Balkans.Semantic proximity Read ↗

IL7RA haplotype-associated alterations in cellular immune function and gene expression patterns in multiple sclerosis.Semantic proximity Read ↗

Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients.Semantic proximity Read ↗

IL7RA polymorphisms and chronic inflammatory arthropathies.Semantic proximity Read ↗

Relevance of IL7R genotype and mRNA expression in Dutch patients with multiple sclerosis.Semantic proximity Read ↗

Association between IL7 Receptor Alpha (Il7ra) gene rs6897932 polymorphism and the risk of Multiple Sclerosis: A meta-regression and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.