Article
Analysis of the C/T(-1) single nucleotide polymorphism in the CD40 gene in multiple sclerosis.
Tissue antigens - 1 Oct 2006
Buck D, Kroner A, Rieckmann P, Mäurer M, Wiendl H
Abstract excerpt
The costimulatory CD40-CD40L pathway plays a critical role in the generation and maintenance of adaptive immune responses. Genetic interference of CD40-CD40L interactions strongly influences the onset and course in many autoimmune disease models including experimental autoimmune encephalomyelitis...
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