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Article

OAS1 gene haplotype confers susceptibility to multiple sclerosis.

Tissue antigens - 1 Nov 2006

Fedetz M, Matesanz F, Caro-Maldonado A, Fernandez O, Tamayo J A, Guerrero M, Delgado C, López-Guerrero J A, Alcina A

Abstract excerpt

Multiple sclerosis (MS) is associated with genetic susceptibility and unknown environmental triggers, possible viral infections, but the specific etiological mechanism that subsequently develops into an inflammatory/autoimmune cascade of events is poorly understood. Recently, genetic variants of 2',5'- oligoadenylate synthetase 1 (OAS1) gene, a critical enzyme involved in innate antivirus response, have been...

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Source

Identifiers

PMID: 17092260
DOI: 10.1111/j.1399-0039.2006.00694.x

Genes

OAS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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