Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in the transforming growth factor beta1 gene in multiple sclerosis.

Journal of neuroimmunology - 1 Nov 2001

Weinshenker B G, Hebrink D, Kantarci O H, Schaefer-Klein J, Atkinson E, Schaid D, McMurray C M

Abstract excerpt

Transforming growth factor beta1 (TGFbeta1) is a Th2 cytokine encoded on chromosome 19q13, a region possibly linked to multiple sclerosis (MS). TGFbeta1 exerts favorable effects on experimental allergic encephalomyelitis. We performed a comprehensive search for genetic variants in this gene in 122 population-based sporadic cases of MS. We detected six variants, including three missense variants. We tested for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 19
Share to Exons
Share to Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Multiple Sclerosis

Share to Mutation, Missense

Share to Transforming Growth Factor beta

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 11694328
DOI: 10.1016/s0165-5728(01)00424-6

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in the transforming growth factor beta1 gene in multiple sclerosis.PMID 11694328Read ↗

Sequence variation in the transforming growth factor-beta1 (TGFB1) gene and multiple sclerosis susceptibility.Semantic proximity Read ↗

Investigation of TGFB2 as a candidate gene in multiple sclerosis and Parkinson's disease.Semantic proximity Read ↗

Gender-related association between the TGFB1+869 polymorphism and multiple sclerosis.Semantic proximity Read ↗

+10 T/C polymorphisms in the gene of transforming growth factor-beta1 are associated with neurodegeneration and its clinical evolution.Semantic proximity Read ↗

A link between promoter polymorphisms of the transforming growth factor β1 (TGFB1) and TGF-β1 receptor II (TGFBR2) genes and relapsing-remitting multiple sclerosis.Semantic proximity Read ↗

Association study of three polymorphisms of TGF-beta1 gene with Alzheimer's disease.Semantic proximity Read ↗

Population frequencies of single nucleotide polymorphisms (SNPs) in immuno-modulatory genes.Semantic proximity Read ↗

Allelic diversity in the TGFB1 regulatory region: characterization of novel functional single nucleotide polymorphisms.Semantic proximity Read ↗

Detection of rare nonsynonymous variants in TGFB1 in otosclerosis patients.Semantic proximity Read ↗

Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.Semantic proximity Read ↗

Genetic variation in the B7-1 gene in patients with multiple sclerosis.Semantic proximity Read ↗

MYO9B polymorphisms in multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.