Article
The interaction of heparin sulfate and adeno-associated virus 2.
Virology - 30 Mar 2000
Qiu J, Handa A, Kirby M, Brown K E
Abstract excerpt
Recently heparan sulfate was proposed as the host cell receptor for the dependovirus, adeno-associated virus type 2 (AAV2). We show that although heparan sulfate on the cell surface may contribute to the binding of AAV2 to permissive cells, the amount of heparan sulfate on the cell surface as determined by flow cytometry using four different monoclonal antibodies does not correlate with AAV2 binding to cells or...
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