Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans.

doi:10.1083/jcb.116.5.1273

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Article

Cell surface receptors for herpes simplex virus are heparan sulfate proteoglycans.

The Journal of cell biology - 1 Mar 1992

Shieh M T, WuDunn D, Montgomery R I, Esko J D, Spear P G

Abstract excerpt

The role of cell surface heparan sulfate in herpes simplex virus (HSV) infection was investigated using CHO cell mutants defective in various aspects of glycosaminoglycan synthesis. Binding of radiolabeled virus to the cells and infection were assessed in mutant and wild-type cells. Virus bound e...

Topics

Animals
CHO Cells
Cricetinae
Gene Expression
Heparitin Sulfate
Mutation
Protein Binding
Proteoglycans
Receptors, Virus
Simplexvirus
Vesicular stomatitis Indiana virus

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