Article
RABR-1, an atypical Rab-related GTPase, cell-nonautonomously restricts somatosensory dendrite branching.
Genetics - 7 Oct 2024
Salazar Christopher J, Diaz-Balzac Carlos A, Wang Yu, Rahman Maisha, Grant Barth D, Bülow Hannes E
Abstract excerpt
Neurons are highly polarized cells with dendrites and axons. Dendrites, which receive sensory information or input from other neurons, often display elaborately branched morphologies. While mechanisms that promote dendrite branching have been widely studied, less is known about the mechanisms that restrict branching. Using the nematode Caenorhabditis elegans, we identify rabr-1 (for Rab-related gene 1) as a...
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