A mosaic genetic screen for genes necessary for Drosophila mushroom body neuronal morphogenesis.

doi:10.1242/dev.00319

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Article

A mosaic genetic screen for genes necessary for Drosophila mushroom body neuronal morphogenesis.

Development (Cambridge, England) - 1 Mar 2003

Reuter John E, Nardine Timothy M, Penton Andrea, Billuart Pierre, Scott Ethan K, Usui Tadao, Uemura Tadashi, Luo Liqun

Abstract excerpt

Neurons undergo extensive morphogenesis during development. To systematically identify genes important for different aspects of neuronal morphogenesis, we performed a genetic screen using the MARCM system in the mushroom body (MB) neurons of the Drosophila brain. Mutations on the right arm of chromosome 2 (which contains approximately 20% of the Drosophila genome) were made homozygous in a small subset of...

Topics

Animals
Axons
Cadherins
Carrier Proteins
Dendrites
Drosophila
Drosophila Proteins
Microfilament Proteins
Mushroom Bodies
Mutation
Neurons

Source

Open in PubMed

Identifiers

PMID: 12571111
DOI: 10.1242/dev.00319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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