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Article

Deletions of chromosome 5q13.3 and 17p loci cooperate in myeloid neoplasms.

Blood - 15 Mar 2000

Castro P D, Liang J C, Nagarajan L

Abstract excerpt

Nonrandom interstitial deletions and monosomy of chromosomes 5, 7, and 17 in refractory myelodysplasia (MDS) and acute myelogenous leukemia (AML) suggest a multistep pathway that culminates in aggressive clinical course. Because cytogenetic studies frequently identify chromosome 5 and 17 deletions within a single clone, we searched for allele loss for 5q loci and TP53 gene mutations in the same leukemic samples....

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PMID: 10706886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletions of chromosome 5q13.3 and 17p loci cooperate in myeloid neoplasms.PMID 10706886Read ↗

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