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Article

p53 gene mutations in sequential oral epithelial dysplasias and squamous cell carcinomas.

The Journal of pathology - 1 Mar 2000

Shahnavaz S A, Regezi J A, Bradley G, Dubé I D, Jordan R C

Abstract excerpt

Previous studies of oral cancer have suggested that alterations of the p53 tumour suppressor gene occur early in the precancerous stage of development. However, these observations have been based on cross-sectional assessment of abnormal p53 protein staining by immunohistochemistry and may not necessarily reflect gene changes. The purpose of this longitudinal study was to examine the changes in the p53 gene in...

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PMID: 10699989
DOI: 10.1002/(SICI)1096-9896(200003)190:4<417::AID-PATH544>3.0.CO;2-G

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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