Article
p53 mutation is rare in oral mucosa brushings from patients previously treated for a head and neck squamous cell carcinoma.
Oral oncology - 1 Aug 2009
Acha-Sagredo Amelia, Ruesga Maria T, Rodriguez Carlos, Aguirregaviria Jose I, de Pancorbo Marian M, Califano Joseph A, Aguirre Jose M
Abstract excerpt
Mutations of the tumour suppressor gene p53 are common in human cancer, and seem to be an early event in head and neck squamous cell carcinomas. The aim of our study was to determine the status of the tumour suppressor gene p53 in the oral mucosa of patients previously treated for a head and neck squamous cell carcinoma, at risk of developing an oral squamous cell carcinoma, but without oral clinical lesions....
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