Article
Longitudinal study of TP53 mutations in eight patients with potentially malignant oral mucosal disorders.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Oct 2009
Ogmundsdóttir H M, Hilmarsdóttir H, Björnsson J, Holbrook W P
Abstract excerpt
OBJECTIVES: In a previous cross-sectional study, the authors found a higher rate of TP53 mutation in oral lichen planus (OLP) than in hyperkeratosis. By analysing for TP53 mutations in serial samples from patients on long-term follow-up of their oral lesions, it was hoped to determine if these mutations were related to disease progression. METHODS: Eight patients presenting with lesions diagnosed clinically as...
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