Article
Recurrent allelic deletions of chromosome arms 15q and 16q in human small cell lung carcinomas.
Genes, chromosomes & cancer - 1 Mar 2000
Stanton S E, Shin S W, Johnson B E, Meyerson M
Abstract excerpt
The genetic lesions that lead to the development of small cell lung carcinoma (SCLC) remain incompletely defined. To identify recurrent allelic deletions in specific chromosomal regions that could serve as markers for tumor suppressor gene (TSG) inactivation in SCLC, we performed a comprehensive allelotype analysis of all 39 nonacrocentric autosomal arms. Alterations in 158 polymorphic microsatellite alleles were...
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